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British Journal of Medicine and Medical Research, ISSN: 2231-0614,Vol.: 13, Issue.: 11

Original-research-article

The Totaled Health Risks in Vascular Events (THRIVE) Score Predicts Ischemic Stroke Outcomes

 

Hesna Bektas1*, Sadiye Gumusyayla2, Gonul Vural2, Asli Bolayir1 and Orhan Deniz2

1Department of Neurology, Atatürk Training and Research Hospital, Ankara, Turkey.

2Department of Neurology, Yıldırım Beyazıt University Medical School, Ankara, Turkey.

Article Information

Editor(s):

(1) Vijay K. Sharma, Division of Neurology, Yong Loo Lin School of Medicine, National University of Singapore, National University Hospital, Singapore.

Reviewers:

(1) Adria Arboix, University of Barcelona, Barcelona, Catalonia, Spain.

(2) Mario Guidotti, Valduce Hospital General Como, Italy.

Complete Peer review History: http://sciencedomain.org/review-history/13352

Abstracts

Objective: Assessment of the outcome after an ischemic stroke is important both to serve as a baseline for the evaluation of therapeutic measures and for rehabilitation and health planning. Our aim was to compare the Total Health Risks in Vascular Events (THRIVE) score with outcome scores and infarct volumes.

Methods: We retrospectively reviewed our stroke registry for the period 12/2012–12/2013 and identified patients diagnosed with ischemic stroke. We included patients who had undergone Diffusion-Weighted Magnetic Resonance Imaging (DW-MRI) within 24 hours of their stroke. One of the investigators reviewed all the DW-MRI images to verify infarct volumes. The periphery of the lesion area in each section was drawn by hand, and the surface area of the section was automatically calculated in mm2 by PACS (Picture Archiving and Communication System software), which was installed on the computer. The areas were summed, and the result was multiplied by the section thickness to calculate infarct volumes. The THRIVE scores were calculated. Infarct volumes and clinical outcomes, as measured by Modified Rankin Scale (mRS) and Barthel Index (BI), were compared to initial THRIVE score subgroups of 0–2 and ≥3.

Results: We included 153 (65 female, 88 male) patients in the study. The mean age was 68.30±12.07 years. The median infarct volume was 4.10 cm3 (Interquartile range (IQR):19.180). An increasing THRIVE score was independently associated with an increasing likelihood of poor outcome (mRS≥3: odds ratio, 2.140; 95% confidence interval, 1.068–4.290; BI<60: odds ratio, 0.335; 95% confidence interval, 0.149–0.751). There was no significant difference in infarct volumes between the THRIVE score subgroups of 0–2 and ≥3 (P=0.43).

Discussion: The THRIVE score is simple to use and predicts long-term neurological outcomes in ischemic stroke patients.

Keywords :

Ischemic stroke; infarct volumes; THRIVE score; outcomes.

Full Article - PDF    Page 1-7

DOI : 10.9734/BJMMR/2016/23887

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